The Interaction Itinerary

In a paper published this week in PLoS Biology, senior author Tim Gardner and his colleagues attempt to validate the performance of machine learning algorithms on the genome scale using E. coli. The team mapped more than 1,000 interactions in the E. coli transcriptional regulatory network using microarrays. They've made the ensuing expression data available here, and anyone interested in checking out the CLR algorithm they used can download it here.