Washington University's David Dooling blogs that the school's genome center kicks off its work for the 1,000 Genomes Project this week. "This project, which aims to create a much deeper understanding of normal human variation, will begin by sequencing DNA from the well-characterized samples of the HapMap Project," he writes. Dooling also describes the three pilot projects planned for the effort, "each of which will generate an unprecedented amount of genomic information," he says.