Ricardo Vidal has a blog post at My Biotech Life about FoldIt, a project from David Baker's lab that puts protein folding into a gaming environment, challenging people to "solve puzzles for science." Ricardo writes that players try to "make the protein fold in the best way possible with points being given for stability through hydrogen bonding, compacting, hydrophobic and hydrophilic positioning of lateral protein chains, etc."
Well, there goes the time GTO was going to spend on Grand Theft Auto IV. So long, Niko Bellic, we've got proteins to fold.